Guide · ADC

Twitch Guide

the Plague Rat

Marksman

Assassin

Tier A ADC

Twitch, the Plague Rat, is a marksman and assassin champion of medium difficulty. Across our 450 analysed ranked games, Twitch is mostly played as ADC (100% of its games), with a 50.4% win rate in that role: tier A among ADC champions (#9 of 36, ranked by win rate). Twitch's damage is mostly physical (79%): armor is the best defensive answer against this champion. 16% of that damage is true damage and therefore ignores resistances. Win rate varies with game length: 55.9% in long games (over 35 min, 68 games) versus 47.2% in short games (under 25 min).

Updated Oct 10 2026 · Patch 26.22

Averages measured over 450 ADC games played with Twitch, from our ranked Solo/Duo data collection.

How to play and combo preview

Twitch is a venom marksman-assassin: his attacks infect the target and deal true damage every second. Ambush camouflages him with a speed bonus, Venom Cask slows and applies poison, Contaminate makes it worse, and Spray and Pray fires bolts that pierce all enemies.

The ambush

Q › AA AA › AA AA › E

When: A carry is within range.

Ambush camouflages you and raises your speed; on leaving it, your attack speed rises: strike then Contaminate worsens the poison.

Harassment

W › AA AA › AA AA

When: An enemy is within range.

Venom Cask explodes in an area, slows and applies Deadly Venom; your attacks reinforce the poison.

See all 3 Twitch combos: key order, when to cast them, cooldowns →

Laning phase

Poison your opponent with attacks then use Contaminate to make it worse. When you leave camouflage, your attack speed briefly rises.

Common mistakes

• Using Contaminate with no poison.
• Casting the ultimate without lining up the enemies.
• Leaving camouflage with no target: you lose your window.

Riot's official tips for playing Twitch

• Twitch's Attack Speed is among the highest in the game; try purchasing items with on-hit effects such as Black Cleaver or Wit's End.
• Contaminate has a large range; apply as many stacks of Deadly Venom as possible before using it.
• You can catch up to an enemy out of attack range with Venom Cask.

Build, runes and summoner spells

The most-played core build is Fiendhunter Bolts, Infinity Edge, and The Collector (142 games, 57.8% win rate).

Fiendhunter Bolts+Infinity Edge+The Collector

142 games · 57.8%

Infinity Edge+Runaan's Hurricane+The Collector

83 games · 62.6%

Infinity Edge+Lord Dominik's Regards+The Collector

81 games · 56.8%

Skill order

Max order : E > Q > W55.7% · 61 games

	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Q	●							●		●		●	●
W			●											●	●
E		●		●	●		●		●
R						●					●

The order shows which abilities reach rank 5 first; the grid shows the most-played level-up sequence with that order (measured over 80 games).

Starting items

Doran's BowHealth PotionHealth Potion56.2% · 48 games

Doran's BladeHealth Potion58.3% · 24 games

First completed items, in order

The Collector›Fiendhunter Bolts›Infinity Edge

22 games · 54.5%

Laning phase (averages)

At 10 min: 3760 gold, 67 CS, 3352 XP. At 15 min: 6221 gold, 101 CS, 5495 XP.

Summoner spells

Flash + Barrier51.2% · 330 games

Exhaust + Flash40.5% · 42 games

Flash + Ghost48.3% · 29 games

Flash + Ignite60.0% · 25 games

Most-played runes

Lethal Tempo + Sorcery

55.4% · 168 games

Primary tree · Precision

Triumph92%

Legend: Alacrity96%

Cut Down92%

Secondary tree · Sorcery

Gathering Storm98%

Axiom Arcanist96%

Shards

Attack speed98%

Adaptive force100%

Health96%

Lethal Tempo + Domination

52.0% · 102 games

Primary tree · Precision

Triumph76%

Legend: Alacrity98%

Coup de Grace65%

Secondary tree · Domination

Sudden Impact96%

Treasure Hunter60%

Shards

Attack speed98%

Adaptive force99%

Health93%

Press the Attack + Sorcery

49.5% · 95 games

Primary tree · Precision

Triumph53%

Legend: Alacrity99%

Cut Down74%

Secondary tree · Sorcery

Gathering Storm98%

Axiom Arcanist57%

Shards

Attack speed98%

Adaptive force99%

Health87%

For each row, the most picked rune among the games played with this page (share of games in brackets).

Which items to build against the enemy team?

We sort every game by the enemy team's damage. These are Twitch's completed items and their win rate in each situation; "▲" marks an item that does at least 3 points better than its usual win rate.

Mostly magic-damage enemy team56.6% · 129 games

At least 50% of their damage is magic

Infinity Edge 62.8% ▲

The Collector 59.5% ▲

Fiendhunter Bolts 53.8%

Runaan's Hurricane 73.3% ▲

Lord Dominik's Regards 71.4% ▲

Yun Tal Wildarrows 56.7% ▲

The item that stands out most is Lord Dominik's Regards: 71.4% win rate, +18 points versus its usual win rate.

Mostly physical-damage enemy team51.2% · 121 games

Less than 35% of their damage is magic

Infinity Edge 53.9%

The Collector 53.3%

Fiendhunter Bolts 55.9% ▲

Runaan's Hurricane 45.3% ▼

Lord Dominik's Regards 48.8% ▼

Yun Tal Wildarrows 39.1%

The item that stands out most is Fiendhunter Bolts: 55.9% win rate, +3 points versus its usual win rate.

Balanced enemy team46.0% · 200 games

Mixed physical and magic damage

Infinity Edge 53.4% ▼

The Collector 43.0% ▼

Runaan's Hurricane 52.3% ▼

Fiendhunter Bolts 50.0%

Lord Dominik's Regards 47.7% ▼

Yun Tal Wildarrows 57.1% ▲

The item that stands out most is Yun Tal Wildarrows: 57.1% win rate, +5 points versus its usual win rate.

Counters and matchups

Who counters Twitch as ADC

Tristana Twitch: 38.9%18 games

Tristana has the edge in 61% of the 18 ADC duels against Twitch. See the Tristana guide.

Jinx Twitch: 40.7%27 games

Jinx has the edge in 59% of the 27 ADC duels against Twitch. See the Jinx guide.

Caitlyn Twitch: 46.7%15 games

Caitlyn has the edge in 53% of the 15 ADC duels against Twitch. See the Caitlyn guide.

Yunara Twitch: 50.0%22 games

Yunara has the edge in 50% of the 22 ADC duels against Twitch. See the Yunara guide.

Kai'Sa Twitch: 58.6%29 games

Kai'Sa has the edge in 41% of the 29 ADC duels against Twitch. See the Kai'Sa guide.

Who Twitch is strong against

Jhin62.5% · 24 games

Kai'Sa58.6% · 29 games

Yunara50.0% · 22 games

Caitlyn46.7% · 15 games

Jinx40.7% · 27 games

How to play against Twitch

• Twitch is fragile. Work with teammates to focus on him when you're able to catch him out of Camouflage.
• Spell Shields won't block the damage from Deadly Venom, but they will block the effects Twitch can trigger with it.
• If you suspect Twitch has left the lane, let your teammates know that Twitch is ''MIA.''

Win rates measured over direct same-role duels; only matchups with more than 15 games are listed. See all of Twitch's matchups.

Twitch ADC: what our games say

Laning phase against the ADC average

Measured over 80 Twitch games with a timeline; the average covers 49 champions played ADC in our ranked games.

Win rate by game length

Best result: long (over 35 min). Only groups of at least 30 games are shown. A gap of several points shows the phase where the champion is the most reliable.

Abilities

PassiveDeadly Venom

Twitch's basic attacks infect the target %i:OnHit% On-Hit, dealing true damage each second.

QAmbush

Twitch becomes Camouflaged for a short duration and gains Move Speed. When leaving Camouflage, Twitch gains Attack Speed for a short duration.

When an enemy champion with Deadly Venom dies, Ambush's cooldown is reset.

WVenom Cask

Twitch hurls a cask of venom that explodes in an area, slowing targets and applying deadly venom to the target.

EContaminate

Twitch wreaks further havoc on poisoned enemies with a blast of his vile diseases.

RSpray and Pray

Twitch unleashes the full power of his crossbow, shooting bolts over a great distance that pierce all enemies caught in their path.

Other ADC champions to know

Most played

Jhin48.5 %Yunara52.4 %Kai'Sa49.9 %Ezreal45.2 %Caitlyn50.3 %Jinx51.0 %Tristana50.0 %Lucian48.9 %

Strongest (at least 100 games)

Brand57.7 %Syndra56.7 %Aurelion Sol56.7 %Kog'Maw55.3 %Senna55.3 %Mel54.9 %Vel'Koz53.8 %Xayah53.1 %

Frequently asked questions

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